Description

(2S,5R)-6-(Benzyloxy)-N'-Formyl-7-Oxo-1,6-Diazabicyclo[3.2.1]Octane-2-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its complex, bicyclic β-lactam-related structure. This compound is of significant value in the research and development of novel antibiotics and enzyme inhibitors, particularly targeting bacterial resistance mechanisms. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in synthetic organic chemistry and medicinal chemistry programs.

Application

• Key Intermediate for Novel β-Lactamase Inhibitors: Serves as a critical building block in the synthesis of next-generation antibacterial agents designed to overcome multidrug-resistant bacterial infections.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of diazabicyclooctane (DBO) core derivatives.
• Process Development & Scale-Up: Employed in pilot-scale and commercial-scale synthesis routes for active pharmaceutical ingredients (APIs) in the anti-infective therapeutic class.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Probe Development: Acts as a precursor for labeled compounds or probes used in enzymatic studies and mechanism-of-action research.

Basic Information

Product Name	(2S,5R)-6-(Benzyloxy)-N'-Formyl-7-Oxo-1,6-Diazabicyclo[3.2.1]Octane-2-Carbohydrazide
CAS No.	1426572-71-5
Molecular Formula	C15H18N4O4
Molecular Weight	318.33 g/mol
Synonyms	(2S,5R)-6-(Benzyloxy)-N'-formyl-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide; 6-(Benzyloxy)-N'-formyl-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide, (2S,5R)-; Diazabicyclooctane DBO intermediate; Avibactam related intermediate; NXL-104 intermediate; AVI-7288 intermediate; β-Lactamase inhibitor intermediate; 1,6-Diazabicyclo[3.2.1]octane-2-carbohydrazide derivative
EINECS	Contact for details

Quality Control

Our (2S,5R)-6-(Benzyloxy)-N'-Formyl-7-Oxo-1,6-Diazabicyclo[3.2.1]Octane-2-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification tests. Certificates of Analysis (COA) detailing all specifications and results are provided to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S,5R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.