Description

3-Iodo-1-Methyl-6-(Trifluoromethyl)-1H-Indazole is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is particularly significant for its trifluoromethyl and iodine substituents, which are crucial for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, such as the development of kinase inhibitors and other bioactive agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs, especially in oncology and CNS diseases.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays due to the reactivity of the iodine moiety.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for electronic materials.

Basic Information

Product Name	3-Iodo-1-Methyl-6-(Trifluoromethyl)-1H-Indazole
CAS No.	1426425-33-3
Molecular Formula	C9H5F3IN2
Molecular Weight	316.05 g/mol
Synonyms	1-Methyl-3-iodo-6-(trifluoromethyl)-1H-indazole; 6-(Trifluoromethyl)-1-methyl-1H-indazol-3-yl iodide; 3-Iodo-1-methyl-6-(trifluoromethyl)indazole; 1-Methyl-6-(trifluoromethyl)-1H-indazol-3-yl iodide; 3-Iodo-1-methyl-6-trifluoromethylindazole
EINECS	Contact for details

Quality Control

Our 3-Iodo-1-Methyl-6-(Trifluoromethyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.