Description

7-Iodoquinazoline is a high-value halogenated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its versatile reactivity, where the iodine atom acts as an excellent handle for cross-coupling reactions, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, especially kinase inhibitors and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: An ideal substrate for Suzuki, Stille, and Sonogashira couplings to introduce the quinazoline core into more complex systems.
• Chemical Biology: Utilized as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Contract Research: A valuable reagent for method development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	7-Iodoquinazoline
CAS No.	1425310-59-3
Molecular Formula	C8H5IN2
Molecular Weight	256.04 g/mol
Synonyms	Quinazoline, 7-iodo-; 7-Iodo-quinazoline; 1425310-59-3; 7-Iodoquinazoline; Quinazoline, 7-iodo; 7-Iodo-1,3-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 7-Iodoquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles for the production of advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.