Description

Methyl (2S,4R)-4-((3-Chloro-7-Methoxyquinoxalin-2-Yl)Oxy)-2-(Methoxycarbonyl)Pyrrolidinium Methanesulfonate is a high-purity, non-racemic chiral building block and advanced pharmaceutical intermediate. This compound is specifically engineered for the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is essential for research and development chemists in the pharmaceutical and agrochemical industries who require a reliable, high-quality intermediate for constructing novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging its quinoxaline core structure.
• Chemical Biology Research: Serves as a probe or precursor in the study of enzyme inhibition and receptor-ligand interactions due to its specific stereochemistry.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the commercial manufacturing of complex organic molecules.
• Custom Synthesis & Contract Manufacturing: A critical component for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl (2S,4R)-4-((3-Chloro-7-Methoxyquinoxalin-2-Yl)Oxy)-2-(Methoxycarbonyl)Pyrrolidinium Methanesulfonate
CAS No.	1425038-20-5
Molecular Formula	C18H22ClN3O7S
Molecular Weight	459.90 g/mol
Synonyms	(2S,4R)-1-Methyl-4-[(3-chloro-7-methoxyquinoxalin-2-yl)oxy]-2-(methoxycarbonyl)pyrrolidinium methanesulfonate; (2S,4R)-Methyl 4-((3-chloro-7-methoxyquinoxalin-2-yl)oxy)-1-methylpyrrolidine-2-carboxylate methanesulfonate; Methyl 4-((3-chloro-7-methoxyquinoxalin-2-yl)oxy)-2-(methoxycarbonyl)-1-methylpyrrolidinium methanesulfonate; UNII-6J5J8V245H; 6J5J8V245H; (2S,4R)-1-Methyl-4-((3-chloro-7-methoxyquinoxalin-2-yl)oxy)pyrrolidine-2-carboxylic acid methyl ester methanesulfonate
EINECS	Contact for details

Quality Control

Our Methyl (2S,4R)-4-((3-Chloro-7-Methoxyquinoxalin-2-Yl)Oxy)-2-(Methoxycarbonyl)Pyrrolidinium Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.