Description

1-(4-Bromobutyl)-3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone CAS NO 1424857-68-0 is a high-purity, advanced pharmaceutical intermediate featuring a bromobutyl side chain and a hydroxyquinolinone core structure. This compound is a critical building block in modern organic synthesis, valued for its versatility in constructing complex molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development and production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Organic Synthesis Building Block: Used in coupling reactions, alkylation, and as a scaffold for constructing fused heterocyclic compounds in medicinal chemistry.
• Research & Development (R&D): Essential for academic and industrial research in exploring new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a critical intermediate in the multi-step synthesis of final drug substances under GMP conditions.
• Chemical Biology Probes: Utilized in the development of labeled compounds and probes for studying biological mechanisms and target identification.

Basic Information

Product Name	1-(4-Bromobutyl)-3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone
CAS No.	1424857-68-0
Molecular Formula	C₁₃H₁₆BrNO₂
Molecular Weight	298.18 g/mol
Synonyms	7-Hydroxy-1-(4-bromobutyl)-3,4-dihydro-2(1H)-quinolinone; 1-(4-Bromobutyl)-7-hydroxy-3,4-dihydroquinolin-2(1H)-one; 7-Hydroxy-1-(4-bromobutyl)-1,2,3,4-tetrahydroquinolin-2-one; 1424857-68-0; Bromobutyl hydroxyquinolinone; 4-Bromobutyl quinolinone derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Bromobutyl)-3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available for every batch and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.