Description

(1S)-7-(Propan-2-Yloxy)-1,2,3,4-Tetrahydronaphthalen-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, a key advanced pharmaceutical intermediate (API) and building block in modern organic synthesis. Its defined stereochemistry and functional groups make it a critical component for developing enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create novel, high-value compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel central nervous system (CNS) active drugs, including potential antidepressants, anti-anxiety agents, and neuroprotective compounds.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological efficacy and environmental safety.
• Asymmetric Synthesis Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis to create other high-value enantiopure compounds.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and as a molecular scaffold for probing biological pathways and identifying new drug candidates.
• Reference Standard: Used as a certified reference material (CRM) or analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Fine Chemical Synthesis: A versatile intermediate for constructing complex polycyclic structures in academic and industrial research settings.

Basic Information

Product Name	(1S)-7-(Propan-2-Yloxy)-1,2,3,4-Tetrahydronaphthalen-1-Amine Hydrochloride
CAS No.	1423040-91-8
Molecular Formula	C₁₃H₂₀ClNO
Molecular Weight	241.76 g/mol
Synonyms	(1S)-7-Isopropoxy-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride; (1S)-7-(Isopropyloxy)-1,2,3,4-tetrahydronaphthalen-1-amine HCl; 1-Amino-7-isopropoxy-1,2,3,4-tetrahydronaphthalene hydrochloride, (1S)-; 7-Isopropoxy-1-tetralinamine hydrochloride, (S)-; (S)-7-(Propan-2-yloxy)-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride; (S)-7-Isopropoxy-1,2,3,4-tetrahydro-1-naphthylamine hydrochloride; 1-Tetralinamine, 7-(1-methylethoxy)-, hydrochloride, (1S)-; (1S)-7-(1-Methylethoxy)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
EINECS	Contact for details

Quality Control

Our production of (1S)-7-(Propan-2-Yloxy)-1,2,3,4-Tetrahydronaphthalen-1-Amine Hydrochloride adheres to stringent quality management systems. The material is manufactured under controlled conditions and undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.