Description

3-Methylpyrrolidin-3-Amine 2Hcl is a high-purity, versatile chiral amine building block, primarily supplied as its dihydrochloride salt for enhanced stability and handling. This compound is critical for the synthesis of complex molecules, offering a rigid pyrrolidine scaffold with a strategically positioned amine and methyl group for fine-tuning molecular interactions. It is an essential intermediate for pharmaceutical R&D, agrochemical development, and advanced material science, where precise stereochemistry and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, where its structural motif can contribute to biological activity and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for designing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: A valuable building block in medicinal chemistry for constructing diverse compound libraries and exploring structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials requiring high-purity intermediates.

Basic Information

Product Name	3-Methylpyrrolidin-3-Amine 2Hcl
CAS No.	1423029-58-6
Molecular Formula	C5H14Cl2N2
Molecular Weight	173.08 g/mol
Synonyms	3-Methyl-3-aminopyrrolidine dihydrochloride; 3-Amino-3-methylpyrrolidine hydrochloride (2:1); 3-Methylpyrrolidin-3-amine dihydrochloride; 3-Methyl-3-pyrrolidinamine dihydrochloride; (3R)-3-Methylpyrrolidin-3-amine dihydrochloride (if enantiomer); (3S)-3-Methylpyrrolidin-3-amine dihydrochloride (if enantiomer); 3-MAP-2HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Methylpyrrolidin-3-Amine 2Hcl is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA), including results for purity (HPLC), chiral purity (if applicable), identity (IR, NMR), and impurity profile, is supplied with each shipment to guarantee reproducible performance and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.