Description

Methyl 5-((8-Methoxy-3,4-Dihydroquinolin-1(2H)-Yl)Methyl)Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers focused on drug discovery and development, particularly in areas requiring sophisticated heterocyclic chemistry. The product is supplied with full analytical documentation to ensure batch-to-batch consistency and support regulatory filings.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for lead optimization and the synthesis of compound libraries targeting various biological pathways.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex molecules containing fused quinoline and thiophene moieties.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for investigative chemistry and method development.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	Methyl 5-((8-Methoxy-3,4-Dihydroquinolin-1(2H)-Yl)Methyl)Thiophene-2-Carboxylate
CAS No.	1423018-14-7
Molecular Formula	C18H19NO3S
Molecular Weight	329.41 g/mol
Synonyms	Methyl 5-[(8-methoxy-1,2,3,4-tetrahydroquinolin-1-yl)methyl]thiophene-2-carboxylate; 1,2,3,4-Tetrahydro-8-methoxy-1-[(5-(methoxycarbonyl)-2-thienyl)methyl]quinoline; 2-Thiophenecarboxylic acid, 5-[(8-methoxy-3,4-dihydro-2H-quinolin-1-yl)methyl]-, methyl ester; Methyl 5-((8-methoxy-3,4-dihydroquinolin-1(2H)-yl)methyl)thiophene-2-carboxylate; 1423018-14-7; Quinoline derivative intermediate; Thiophene-quinoline hybrid compound
EINECS	Contact for details

Quality Control

Our Methyl 5-((8-Methoxy-3,4-Dihydroquinolin-1(2H)-Yl)Methyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with stringent purity and identity specifications. Certificates of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.