Description

Pra-Nh2·Tfa CAS NO 1423017-95-1 is a high-purity, trifluoroacetic acid (TFA) protected amine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a protected amine functionality that is stable under a wide range of reaction conditions, yet can be selectively deprotected when needed. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for peptide mimetics and small molecule drugs.
• Peptide Chemistry: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and insecticides requiring specific amine functionalities.
• Ligand and Catalyst Synthesis: Precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Monomer or modifier in the production of advanced polymers and functional materials.
• Chemical Biology: Tool compound for probing biological systems and developing biochemical probes.

Basic Information

Product Name	Pra-Nh2·Tfa
CAS No.	1423017-95-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pra-NH2 TFA; Pra-NH2 Trifluoroacetate; 1-Pyreneamine, Trifluoroacetate Salt; 1-Aminopyrene Trifluoroacetate; 1-Pyrenamine TFA Salt; TFA-protected 1-Aminopyrene; 1-Pyreneammonium Trifluoroacetate
EINECS	Contact for details

Quality Control

Our Pra-Nh2·Tfa is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.