Description

8-Chloro-7-Methoxyquinoline is a high-purity, synthetically valuable quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an indispensable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for antimalarial, anticancer, and antimicrobial agents.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides due to its bioactive quinoline core.
• Material Science: Serves as a building block for creating organic ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Synthesis: A versatile reagent for introducing the 8-chloro-7-methoxyquinoline moiety into more complex molecules via cross-coupling and functional group transformations.
• Academic & Industrial R&D: Essential for methodological studies and discovery chemistry in both university and corporate research laboratories.

Basic Information

Product Name	8-Chloro-7-Methoxyquinoline
CAS No.	1422978-91-3
Molecular Formula	C₁₀H₈ClNO
Molecular Weight	193.63 g/mol
Synonyms	7-Methoxy-8-chloroquinoline; 8-Chloro-7-methoxy-quinoline; Quinoline, 8-chloro-7-methoxy-; 8-Chloro-7-methoxy-chinolin
EINECS	Contact for details

Quality Control

Our 8-Chloro-7-Methoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.