Description

Quinoline, 2,4-Dichloro-6-(Trifluoromethoxy)- is a specialized halogenated quinoline derivative, a high-value building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a quinoline core with chloro and trifluoromethoxy substituents, making it a critical intermediate for creating compounds with tailored electronic and biological properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients, functional materials, and ligands for catalysis. The compound is supplied with a CAS Registry Number of 1422496-24-9.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances bioactivity and environmental stability.
• Material Science: Acts as a building block for organic electronic materials, such as charge-transport layers in OLEDs or semiconductors, due to its electron-deficient quinoline structure.
• Coordination Chemistry & Catalysis: Employed as a ligand precursor for metal-organic frameworks (MOFs) or transition metal catalysts, where its nitrogen donor atoms and halogen groups allow for precise tuning of catalytic activity.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinoline motifs into larger molecular architectures for various R&D purposes.

Basic Information

Product Name	Quinoline, 2,4-Dichloro-6-(Trifluoromethoxy)-
CAS No.	1422496-24-9
Molecular Formula	C₁₀H₄Cl₂F₃NO
Molecular Weight	282.05 g/mol
Synonyms	2,4-Dichloro-6-(trifluoromethoxy)quinoline; 6-(Trifluoromethoxy)-2,4-dichloroquinoline; 2,4-Dichloro-6-trifluoromethoxyquinoline; Quinoline, 2,4-dichloro-6-(trifluoromethoxy)-; 1422496-24-9
EINECS	Contact for details

Quality Control

Our Quinoline, 2,4-Dichloro-6-(Trifluoromethoxy)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC-MS, and NMR, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles. Our quality systems are designed to support research and development as well as scale-up activities, ensuring consistent and reliable material for your critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.