Description

cis-tert-Butyl 3,3A,4,5-Tetrahydro-1H-Pyrrolo[3,4-C]Quinoline-2(9Bh)-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing novel chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Serves in the process development and scale-up stages for new Active Pharmaceutical Ingredients, requiring high chemical purity and consistency.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	cis-tert-Butyl 3,3A,4,5-Tetrahydro-1H-Pyrrolo[3,4-C]Quinoline-2(9Bh)-Carboxylate
CAS No.	1422344-51-1
Molecular Formula	C16H20N2O2
Molecular Weight	272.35 g/mol
Synonyms	tert-Butyl (3aR,9bS)-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,4-c]quinoline-2-carboxylate; (3aR,9bS)-2-(tert-Butoxycarbonyl)-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,4-c]quinoline; cis-2-(tert-Butoxycarbonyl)-1,2,3,3a,4,5-hexahydropyrrolo[3,4-c]quinoline; BOC-protected pyrroloquinoline; cis-Boc-pyrroloquinoline; 1422344-51-1; Pyrrolo[3,4-c]quinoline-2-carboxylic acid, 1,3,3a,4,5,9b-hexahydro-, 1,1-dimethylethyl ester, (3aR,9bS)-
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl 3,3A,4,5-Tetrahydro-1H-Pyrrolo[3,4-C]Quinoline-2(9Bh)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.