Description

2-Benzyl-7-(Bromomethyl)-2,4,5,7-Tetrahydropyrano[3,4-C]Pyrazole CAS NO 1422344-46-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused pyranopyrazole scaffold. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• API Development: Integral to the process development and scale-up of novel Active Pharmaceutical Ingredients (APIs), especially those with fused heterocyclic core structures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and bioorganic chemistry.

Basic Information

Product Name	2-Benzyl-7-(Bromomethyl)-2,4,5,7-Tetrahydropyrano[3,4-C]Pyrazole
CAS No.	1422344-46-4
Molecular Formula	C14H15BrN2O
Molecular Weight	307.19 g/mol
Synonyms	2-Benzyl-7-(bromomethyl)-2,4,5,7-tetrahydropyrano[3,4-c]pyrazole; 2,4,5,7-Tetrahydropyrano[3,4-c]pyrazole, 2-benzyl-7-(bromomethyl)-; 7-(Bromomethyl)-2-benzyl-2,4,5,7-tetrahydropyrano[3,4-c]pyrazole; Pyrano[3,4-c]pyrazole, 2-benzyl-7-(bromomethyl)-2,4,5,7-tetrahydro-; CAS 1422344-46-4
EINECS	Contact for details

Quality Control

Our production of 2-Benzyl-7-(Bromomethyl)-2,4,5,7-Tetrahydropyrano[3,4-C]Pyrazole adheres to stringent quality protocols suitable for pharmaceutical R&D and pre-clinical development. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality management system and can support development projects requiring GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.