Description

2-(3-Fluorophenyl)-2,7-Diazaspiro[4.4]Nonan-3-One is a high-value, spirocyclic organic compound featuring a diazaspiro[4.4]nonane core, which is a privileged scaffold in modern medicinal chemistry. This compound serves as a critical pharmaceutical intermediate and building block for the research and development of novel therapeutic agents. It is primarily sought after by R&D teams in the pharmaceutical, biotechnology, and agrochemical sectors for constructing complex molecules targeting central nervous system disorders, oncology, and other disease areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Building Block: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical entities.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or warhead design for targeted protein degradation therapeutics.
• Agrochemical Research: Employed in the synthesis of new active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for studying biological pathways and target validation.
• Academic & Contract Research: Essential for fundamental research in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	2-(3-Fluorophenyl)-2,7-Diazaspiro[4.4]Nonan-3-One
CAS No.	1422063-12-4
Molecular Formula	C14H16FN2O
Molecular Weight	247.29 g/mol
Synonyms	2-(3-Fluorophenyl)-2,7-diazaspiro[4.4]nonan-3-one; 2,7-Diazaspiro[4.4]nonan-3-one, 2-(3-fluorophenyl)-; 1422063-12-4; 3-Fluorophenyl diazaspiro[4.4]nonanone; 2-(3-Fluorophenyl)-2,7-diazaspiro[4.4]nonane-3-one; Spiro[diazacyclopentane-1,1'-cyclobutane] derivative
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)-2,7-Diazaspiro[4.4]Nonan-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent chemical identity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.