Description

(5S,9S)-9-Phenyl-2-(Pyridin-3-Ylmethyl)-2,7-Diazaspiro[4.4]Nonan-1-One is a sophisticated spirocyclic compound that serves as a critical pharmacological building block and advanced intermediate in modern organic synthesis. Its unique three-dimensional structure and functional groups make it highly valuable for constructing complex molecules with specific biological activity. This compound is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Development: Serves as a precursor for creating selective ligands for various receptor subtypes.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry: Intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Employed in universities and research institutes for methodological studies in heterocyclic and spirocyclic chemistry.

Basic Information

Product Name	(5S,9S)-9-Phenyl-2-(Pyridin-3-Ylmethyl)-2,7-Diazaspiro[4.4]Nonan-1-One
CAS No.	1422062-44-9
Molecular Formula	C23H25N3O
Molecular Weight	359.47 g/mol
Synonyms	9-Phenyl-2-(3-pyridinylmethyl)-2,7-diazaspiro[4.4]nonan-1-one, (5S,9S)-; 2,7-Diazaspiro[4.4]nonan-1-one, 9-phenyl-2-(3-pyridinylmethyl)-, (5S,9S)-; (5S,9S)-9-Phenyl-2-(3-pyridylmethyl)-2,7-diazaspiro[4.4]nonan-1-one; Spirocyclic Pyridinylmethyl Diazanone Derivative; (5S,9S)-enantiomer of 1422062-44-9
EINECS	Contact for details

Quality Control

Our (5S,9S)-9-Phenyl-2-(Pyridin-3-Ylmethyl)-2,7-Diazaspiro[4.4]Nonan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development with custom synthesis and scale-up services under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.