Description

5-(Aminomethyl)Isoindolin-1-One Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant synthetic utility. Its value lies in its functionalized isoindolinone core, which serves as a versatile scaffold for constructing complex molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Synthesis: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Development: The primary amine functionality allows for conjugation to fluorophores, biotin, or other molecules for biochemical probe creation.
• Chemical Biology: Employed in the development of tool compounds and inhibitors for studying biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom fine chemicals.

Basic Information

Product Name	5-(Aminomethyl)Isoindolin-1-One Hydrochloride
CAS No.	1422057-35-9
Molecular Formula	C9H11ClN2O
Molecular Weight	198.65 g/mol
Synonyms	1-Isoindolinone, 5-(aminomethyl)-, hydrochloride; 5-(Aminomethyl)-1-isoindolinone hydrochloride; 5-(Aminomethyl)isoindolin-1-one HCl; 1H-Isoindol-1-one, 5-(aminomethyl)-, hydrochloride; 1422057-35-9; 5-(Aminomethyl)phthalimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)Isoindolin-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.