Description

Benzoic Acid, 4,4',4'',4'''-[1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetrayltetrakis(Methylene)]Tetrakis- is a sophisticated macrocyclic ligand derivative, specifically a tetra-substituted benzoic acid functionalized cyclen. This compound matters as a high-value chelating agent and building block for advanced materials, offering precise metal coordination properties essential for creating functional complexes. It is primarily needed by researchers and manufacturers in the pharmaceutical, diagnostic imaging, and materials science sectors for developing targeted contrast agents, catalysts, and supramolecular assemblies.

Application

• Contrast Agent Precursor: Key intermediate in the synthesis of gadolinium-based MRI contrast agents for medical diagnostics.
• Catalyst Ligand: Serves as a multidentate ligand for transition metal catalysts used in organic synthesis and polymerization reactions.
• Radiopharmaceuticals: Chelating scaffold for binding radioisotopes (e.g., 64Cu, 68Ga) for Positron Emission Tomography (PET) imaging and targeted radiotherapy.
• Supramolecular Chemistry: Building block for constructing complex molecular cages, sensors, and host-guest systems.
• Metal Ion Separation: Used in analytical chemistry and hydrometallurgy for selective extraction and sensing of specific metal ions.
• Bioconjugation: Functional handle for attaching metal complexes to antibodies, peptides, or other biomolecules for targeted applications.

Basic Information

Item	Details
Product Name	Benzoic Acid, 4,4',4'',4'''-[1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetrayltetrakis(Methylene)]Tetrakis-
CAS No.	1421944-62-8
Molecular Formula	C48H52N4O8
Molecular Weight	812.95 g/mol
Synonyms	1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayltetrakis(methylene) tetrakis(4-benzoic acid); Tetra(p-carboxybenzyl)cyclen; DO4A-tetra(p-carboxybenzyl); 1,4,7,10-Tetrakis(carboxymethylbenzyl)-1,4,7,10-tetraazacyclododecane; Cyclen-tetrabenzoic acid derivative; 12-Tetrabenzyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetrabenzyl ester precursor; TBC-cyclen; 4,4',4'',4'''-(Cyclen-1,4,7,10-tetrayltetramethylene)tetrabenzoic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4,4',4'',4'''-[1,4,7,10-Tetraazacyclododecane-1,4,7,10-Tetrayltetrakis(Methylene)]Tetrakis- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.