Description

3-(4-Fluoro-Phenyl)-6A-Pyrrolidin-1-Yl-2,5,6,6A-Tetrahydro-1-Oxa-2,4-Diaza-Pentalene-4-Carboxylic Acid tert-Butyl Ester is a sophisticated heterocyclic building block and advanced pharmaceutical intermediate designed for high-value synthesis. This compound is critical for medicinal chemistry research and development, particularly in constructing complex molecular architectures with targeted biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of complex, high-purity compounds on a commercial scale.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-6A-Pyrrolidin-1-Yl-2,5,6,6A-Tetrahydro-1-Oxa-2,4-Diaza-Pentalene-4-Carboxylic Acid tert-Butyl Ester
CAS No.	1421312-03-9
Molecular Formula	C21H26FN3O3
Molecular Weight	387.45 g/mol
Synonyms	tert-Butyl 3-(4-fluorophenyl)-6a-(pyrrolidin-1-yl)-2,5,6,6a-tetrahydro-1-oxa-2,4-diazapentalene-4-carboxylate; 1-Oxa-2,4-diazapentalene-4-carboxylic acid, 3-(4-fluorophenyl)-2,5,6,6a-tetrahydro-6a-(1-pyrrolidinyl)-, 1,1-dimethylethyl ester; 1421312-03-9; BLD-0409; AKOS025247315; F2147-7245; 3-(4-Fluorophenyl)-6a-(pyrrolidin-1-yl)-2,5,6,6a-tetrahydro-1-oxa-2,4-diazapentalene-4-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-6A-Pyrrolidin-1-Yl-2,5,6,6A-Tetrahydro-1-Oxa-2,4-Diaza-Pentalene-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.