Description

(S)-3-Amino-4-(4-Methoxy-Phenyl)-Butyric Acid-Hcl CAS NO 1421258-68-5 is a high-purity chiral amino acid derivative, specifically the hydrochloride salt of a phenylalanine analog with a methoxy substituent. This compound serves as a critical pharmaceutical intermediate and building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other chiral drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly in oncology and metabolic disease research.
• Peptide Synthesis: Used as a protected or modified amino acid building block for solid-phase and solution-phase peptide synthesis.
• Enzyme Inhibitor Development: Serves as a core structure for designing potent and selective enzyme inhibitors due to its specific stereochemistry and functional groups.
• Chemical Biology Research: Employed in the study of biological pathways and as a tool compound for probing protein-ligand interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Reference Standard: Sourced for analytical purposes, including method development and quality control as a high-purity chemical reference standard.

Basic Information

Product Name	(S)-3-Amino-4-(4-Methoxy-Phenyl)-Butyric Acid Hydrochloride
CAS No.	1421258-68-5
Molecular Formula	C11H16ClNO3
Molecular Weight	245.70 g/mol
Synonyms	(S)-3-Amino-4-(4-methoxyphenyl)butanoic acid hydrochloride; (3S)-3-Amino-4-(4-methoxyphenyl)butanoic acid hydrochloride; L-3-Amino-4-(4-methoxyphenyl)butyric acid HCl; 4-(4-Methoxyphenyl)-L-homo-β-alanine hydrochloride; (S)-Homo-4-methoxy-phenylalanine hydrochloride; (S)-3-Amino-4-(p-methoxyphenyl)butyric acid HCl; AB-1/34567890 (example research code); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of (S)-3-Amino-4-(4-Methoxy-Phenyl)-Butyric Acid-Hcl adheres to stringent in-process controls and final release testing. We provide material that meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available for every batch. Our quality system supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.