Description

Cyclopropyl-Methyl-(S)-Piperidin-3-Yl-Amine Hydrochloride is a high-purity chiral amine salt, a crucial building block in modern pharmaceutical synthesis. Its value lies in its defined stereochemistry and functional group compatibility, enabling the efficient construction of complex, biologically active molecules. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities with potential therapeutic effects.
• Process Chemistry & Scale-Up: Serves as a critical starting material or intermediate in the development of scalable, GMP-compliant synthetic routes for clinical trial material and commercial API manufacturing.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in enantioselective synthesis to introduce the (S)-piperidinyl moiety into target molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	Cyclopropyl-Methyl-(S)-Piperidin-3-Yl-Amine Hydrochloride
CAS No.	1421049-58-2
Molecular Formula	C10H20N2•HCl
Molecular Weight	204.74 g/mol
Synonyms	(S)-1-Cyclopropyl-N-methylpiperidin-3-amine hydrochloride; (S)-1-Cyclopropyl-N-methyl-3-piperidinamine hydrochloride; (3S)-1-Cyclopropyl-N-methyl-3-piperidinamine hydrochloride; (S)-1-Cyclopropyl-N-methylpiperidin-3-amine HCl; (S)-N-Methyl-1-cyclopropylpiperidin-3-amine hydrochloride; CPMPA hydrochloride; (S)-CPMPA HCl
EINECS	Contact for details

Quality Control

Our Cyclopropyl-Methyl-(S)-Piperidin-3-Yl-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to protect from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.