Description

4-(3-Fluoro-Benzenesulfinylmethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a fluorinated benzenesulfinylmethyl moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperidine and sulfoxide functional groups.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for preclinical and clinical trial material production.
• Chemical Biology Probes: Can be utilized in the development of molecular probes to study biological pathways and protein function.

Basic Information

Product Name	4-(3-Fluoro-Benzenesulfinylmethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1420873-25-1
Molecular Formula	C18H26FNO3S
Molecular Weight	355.47 g/mol
Synonyms	1-Boc-4-[(3-fluorophenyl)sulfinylmethyl]piperidine; tert-Butyl 4-{[(3-fluorophenyl)sulfinyl]methyl}piperidine-1-carboxylate; 4-[(3-Fluorophenyl)sulfinylmethyl]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(3-fluorophenyl)sulfinylmethyl]piperidine; N-Boc-4-((3-fluorophenyl)sulfinylmethyl)piperidine; 1420873-25-1; Piperidine-1-carboxylic acid, 4-[(3-fluorophenyl)sulfinylmethyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(3-Fluoro-Benzenesulfinylmethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.