Description

1-(Pyrimidin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride is a high-purity organic salt, primarily utilized as a key pharmaceutical intermediate and building block in medicinal chemistry. Its value lies in its role as a versatile precursor for the synthesis of complex molecules, particularly in drug discovery and development programs targeting various therapeutic areas. This compound is essential for research and production teams in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in the design and construction of novel chemical entities for screening against biological targets.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme function and cellular pathways.
• Library Synthesis for Drug Discovery: Employed in parallel and combinatorial chemistry to create diverse compound libraries for high-throughput screening.
• Process Chemistry & Scale-up: Used in route scouting and optimization for the efficient, large-scale production of candidate drugs.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Product Name	1-(Pyrimidin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride
CAS No.	1420810-39-4
Molecular Formula	C8H13N5 • 2HCl
Molecular Weight	268.15 g/mol
Synonyms	3-Amino-1-(2-pyrimidinyl)pyrrolidine dihydrochloride; 1-(Pyrimidin-2-yl)pyrrolidin-3-amine hydrochloride (1:2); Pyrrolidine, 3-amino-1-(2-pyrimidinyl)-, dihydrochloride; 1420810-39-4; 1-(2-Pyrimidinyl)-3-aminopyrrolidine dihydrochloride; 3-Amino-1-(pyrimidin-2-yl)pyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyrimidin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.