Description

2-Azaspiro[3.3]heptane hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is of significant commercial interest due to its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is primarily utilized by pharmaceutical R&D departments, contract research/manufacturing organizations (CROs/CMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand and Probe Synthesis: Employed in the development of chemical probes and ligands for biological target validation and assay development.
• Agrochemical Development: Serves as a building block for novel crop protection agents and pesticides requiring specific stereochemistry.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	2-Azaspiro[3.3]heptane Hydrochloride
CAS No.	1420271-08-4
Molecular Formula	C6H12ClN
Molecular Weight	133.62 g/mol
Synonyms	2-Azaspiro[3.3]heptane HCl; 2-Azaspiro[3.3]heptane hydrochloride; 2-Aza-spiro[3.3]heptane hydrochloride; 1-Azabicyclo[3.1.0]hexane hydrochloride; 2-Azaspiro[3.3]heptane monohydrochloride; Azaspiroheptane hydrochloride; Spiro[cyclopropane-1,2'-pyrrolidine] hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[3.3]heptane hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.