Description

2-Hydroxy-2-Methyl-8-Azabicyclo[3.2.1]Octane is a specialized bicyclic organic compound featuring a tertiary alcohol and a bridged tertiary amine within its unique molecular framework. This structure makes it a valuable and versatile intermediate for advanced pharmaceutical synthesis and fine chemical research. It is particularly sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those with tropane or related alkaloid-like structures.
• Chiral Auxiliary/Synthon: Utilized in asymmetric synthesis to introduce stereochemical complexity into target molecules.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, insecticides, or plant growth regulators with specific biological activity.
• Ligand Synthesis: Used to create novel nitrogen-containing ligands for catalysis and metal complexation.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for electronics, materials science, and diagnostics.
• Academic & Industrial R&D: A critical reagent for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2-Hydroxy-2-Methyl-8-Azabicyclo[3.2.1]Octane
CAS No.	1419101-14-6
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	2-Methyl-8-azabicyclo[3.2.1]octan-2-ol; 8-Azabicyclo[3.2.1]octan-2-ol, 2-methyl-; 2-Methyl-2-hydroxy-8-azabicyclo[3.2.1]octane; 2-Hydroxy-2-methyl-8-azoniabicyclo[3.2.1]octane (tautomer); 2-Methyl-8-azoniabicyclo[3.2.1]octan-2-olate; Tropane-2-ol, 2-methyl- (related structure); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-Methyl-8-Azabicyclo[3.2.1]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.