Description

2-Chloro-4-Bromo-5-(Trifluoromethoxy)-Benzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery for introducing halogen and trifluoromethoxy substituents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its specific halogen pattern enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and liquid crystals, leveraging its aromatic and halogenated structure.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to niche market demands.

Basic Information

Product Name	2-Chloro-4-Bromo-5-(Trifluoromethoxy)-Benzoic Acid
CAS No.	1419075-84-5
Molecular Formula	C8H3BrClF3O3
Molecular Weight	318.46 g/mol
Synonyms	5-(Trifluoromethoxy)-2-chloro-4-bromobenzoic acid; 2-Chloro-4-bromo-5-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-chloro-4-bromo-5-(trifluoromethoxy)-; 4-Bromo-2-chloro-5-(trifluoromethoxy)benzoic acid; 2-Chloro-4-bromo-α,α,α-trifluoro-m-anisic acid; CAS 1419075-84-5
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Bromo-5-(Trifluoromethoxy)-Benzoic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical intermediate use, and we can accommodate specific customer testing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.