Description

(S)-1-(4-Fluorophenyl)Ethylamine (Hydrochloride) is a high-purity chiral amine building block essential for the synthesis of advanced pharmaceutical intermediates and active ingredients. Its defined stereochemistry and fluorinated aromatic ring make it a critical component in developing targeted therapeutics with enhanced metabolic stability and receptor selectivity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas requiring enantiomerically pure amines.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically enriched compounds.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with specific chiral activity.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Diagnostic Agent Precursor: Potential use in synthesizing radiolabeled compounds or contrast agents for medical imaging.
• Fine Chemical Synthesis: A versatile intermediate for creating complex molecules in academic and industrial research settings.

Basic Information

Product Name	(S)-1-(4-Fluorophenyl)Ethylamine (Hydrochloride)
CAS No.	1419073-74-7
Molecular Formula	C8H11ClFN
Molecular Weight	175.63 g/mol
Synonyms	(S)-1-(4-Fluorophenyl)ethanamine hydrochloride; (S)-α-Methyl-4-fluorobenzylamine hydrochloride; (S)-(-)-1-(4-Fluorophenyl)ethylamine hydrochloride; (1S)-1-(4-Fluorophenyl)ethan-1-amine hydrochloride; (S)-4'-Fluoro-α-methylbenzylamine hydrochloride; (S)-1-(p-Fluorophenyl)ethylamine HCl; (S)-FMEA HCl
EINECS	Contact for details

Quality Control

Our (S)-1-(4-Fluorophenyl)Ethylamine (Hydrochloride) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) verification. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.