Description

C-(5'-Bromo-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Yl)-Methylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1417794-58-1. This compound is a critical building block in the synthesis of complex molecules, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily utilized in the research and development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry and process development for the life sciences industry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its functionalized bipyridinyl scaffold.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the pilot-scale and commercial-scale synthesis of target APIs, ensuring batch-to-batch consistency.
• Bioconjugation & Probe Development: The amine hydrochloride moiety and bromo substituent make it suitable for further derivatization in creating biochemical probes or labeled compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	C-(5'-Bromo-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Yl)-Methylamine Hydrochloride
CAS No.	1417794-58-1
Molecular Formula	C12H17BrClN3
Molecular Weight	318.64 g/mol
Synonyms	4-(Aminomethyl)-5'-bromo-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine] hydrochloride; (5'-Bromo-3,4,5,6-tetrahydro-2H-[1,2'-bipyridin]-4-yl)methanamine hydrochloride; 5'-Bromo-4-(aminomethyl)-3,4,5,6-tetrahydro-2H-[1,2'-bipyridine] hydrochloride; 1417794-58-1; 4-(Aminomethyl)-5'-bromo-1,2,3,6-tetrahydro-2,2'-bipyridine hydrochloride
EINECS	Contact for details

Quality Control

Our C-(5'-Bromo-3,4,5,6-Tetrahydro-2H-[1,2']Bipyridinyl-4-Yl)-Methylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and safety parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.