Description

4-(6-Nitro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic quinoxaline and piperidine structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block in the synthesis of novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors due to the quinoxaline moiety's affinity for ATP-binding sites.
• Chemical Biology Probes: Utilized in the development of chemical probes to study biological processes and protein function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(6-Nitro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1417793-38-4
Molecular Formula	C18H23N5O4
Molecular Weight	373.41 g/mol
Synonyms	tert-Butyl 4-[(6-nitroquinoxalin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(6-nitro-2-quinoxalinyl)amino]piperidine; 4-[(6-Nitroquinoxalin-2-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(6-nitroquinoxalin-2-yl)amino]piperidine; BOC-4-(6-Nitro-quinoxalin-2-ylamino)-piperidine; 1417793-38-4; 4-(6-Nitro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 4-(6-Nitro-Quinoxalin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.