Description

5-(Pyrimidin-5-Yl)Isophthalic Acid is a high-purity, multifunctional aromatic dicarboxylic acid derivative, distinguished by its pyrimidine substituent. This compound is a critical advanced pharmaceutical intermediate and a versatile organic building block for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting specific biological pathways.
• Ligand & Chelator Synthesis: Used to create novel polydentate ligands for metal-organic frameworks (MOFs), catalysts, and diagnostic imaging agents.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polyamides, polyesters, and other specialty polymers with enhanced thermal or mechanical properties.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Electronic Materials: A building block for electron-deficient π-conjugated systems used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized as a linker component in bifunctional molecules for targeted protein degradation.

Basic Information

Product Name	5-(Pyrimidin-5-Yl)Isophthalic Acid
CAS No.	1417570-15-0
Molecular Formula	C12H8N2O4
Molecular Weight	244.20 g/mol
Synonyms	5-(5-Pyrimidinyl)isophthalic acid; 1,3-Benzenedicarboxylic acid, 5-(5-pyrimidinyl)-; Isophthalic acid, 5-(5-pyrimidinyl)-; 5-(Pyrimidin-5-yl)benzene-1,3-dicarboxylic acid; AI3-71477; BCP34515; ZINC000103830757; SCHEMBL21828027
EINECS	Contact for details

Quality Control

Our 5-(Pyrimidin-5-Yl)Isophthalic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.