Description

Benzene, 1-Bromo-3-Nitro-2-(Trifluoromethoxy)- is a specialized halogenated nitrobenzene derivative, distinguished by its unique trifluoromethoxy substituent. This compound is a high-value chemical intermediate prized for its role in synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in the life sciences and fine chemicals sectors who require precise building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, or organic electronic materials due to its electron-withdrawing nitro and halogen groups.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex aromatic systems.
• Dye and Pigment Intermediate: Facilitates the creation of specialized colorants and functional dyes with specific light-absorption properties.

Basic Information

Product Name	Benzene, 1-Bromo-3-Nitro-2-(Trifluoromethoxy)-
CAS No.	1417567-59-9
Molecular Formula	C7H3BrF3NO3
Molecular Weight	285.00 g/mol
Synonyms	1-Bromo-3-nitro-2-(trifluoromethoxy)benzene; 2-Bromo-6-nitro-1-(trifluoromethoxy)benzene; 2-Bromo-6-nitro-α,α,α-trifluoroanisole; 1-Bromo-3-nitro-2-(trifluoromethoxy)benzene; Benzene, 1-bromo-3-nitro-2-(trifluoromethoxy)-; 3-Nitro-2-(trifluoromethoxy)bromobenzene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-Bromo-3-Nitro-2-(Trifluoromethoxy)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.