Description

5-Piperidin-4-Yl-4H-1,2,4-Triazol-3-Amine Dihydrochloride is a high-purity organic salt compound, serving as a critical building block in advanced pharmaceutical research and development. Its value lies in its role as a versatile intermediate for synthesizing novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery pipelines. This compound is essential for medicinal chemists and R&D departments in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new molecular entities.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic molecules.
• CNS Drug Discovery: Serves as a core scaffold for compounds targeting neurological and psychiatric disorders.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other anti-cancer agents.
• Chemical Biology: Useful as a probe or tool compound for studying biological mechanisms and target validation.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	5-Piperidin-4-Yl-4H-1,2,4-Triazol-3-Amine Dihydrochloride
CAS No.	1417363-65-5
Molecular Formula	C7H14N6 · 2HCl
Molecular Weight	279.15 g/mol (for dihydrochloride salt)
Synonyms	5-(Piperidin-4-yl)-4H-1,2,4-triazol-3-amine dihydrochloride; 4H-1,2,4-Triazol-3-amine, 5-(4-piperidinyl)-, dihydrochloride; 5-(4-Piperidyl)-1,2,4-triazol-3-ylamine dihydrochloride; 5-(Piperidin-4-yl)-1H-1,2,4-triazol-3-amine dihydrochloride; 1417363-65-5
EINECS	Contact for details

Quality Control

Our 5-Piperidin-4-Yl-4H-1,2,4-Triazol-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.