Description

6-Bromo-8-(Trifluoromethyl)Imidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its core value lies in the strategic combination of bromo and trifluoromethyl substituents on the imidazopyridine scaffold, offering versatile reactivity and unique physicochemical properties for molecular design. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and CNS-active compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry: The trifluoromethyl group provides a source of fluorine for further functionalization, aiding in the modulation of lipophilicity and bioavailability.

Basic Information

Product Name	6-Bromo-8-(Trifluoromethyl)Imidazo[1,2-A]Pyridine
CAS No.	1417334-55-4
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	6-Bromo-8-(trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-bromo-8-(trifluoromethyl)-; 1417334-55-4; 6-Bromo-8-trifluoromethylimidazo[1,2-a]pyridine; 8-Trifluoromethyl-6-bromoimidazo[1,2-a]pyridine; 6-Bromo-8-(trifluoromethyl)-imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-(Trifluoromethyl)Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.