Description

(R)-tert-Butyl 4-Ethyl-1,2,3-Oxathiazolidine-3-Carboxylate 2,2-Dioxide is a high-purity chiral building block and synthetic intermediate of significant importance in advanced pharmaceutical research and development. Its primary value lies in its role as a key precursor for the synthesis of complex, biologically active molecules, particularly those requiring specific stereochemistry. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Used as a building block to introduce the (R)-configured oxathiazolidine dioxide moiety, which can act as a chiral auxiliary or a protected form of a functional group in complex organic transformations.
• Process Chemistry & Scale-up: Serves as a validated intermediate for the development and optimization of scalable, cost-effective manufacturing routes for target molecules under Good Manufacturing Practice (GMP) guidelines.
• Agrochemical Research: Employed in the discovery and synthesis of new chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Academic & Contract Research: A valuable reagent for universities and Contract Research Organizations (CROs) conducting research in synthetic methodology, medicinal chemistry, and total synthesis of natural products.
• Custom Synthesis & Catalog Supply: Supplied to fine chemical catalogs and used as a starting point for custom synthesis projects requiring specialized, high-value intermediates.

Basic Information

Product Name	(R)-tert-Butyl 4-Ethyl-1,2,3-Oxathiazolidine-3-Carboxylate 2,2-Dioxide
CAS No.	1417287-40-1
Molecular Formula	C9H17NO5S
Molecular Weight	251.30 g/mol
Synonyms	(R)-4-Ethyl-1,2,3-oxathiazolidine-3-carboxylic acid 2,2-dioxide, 1,1-dimethylethyl ester; (R)-tert-Butyl 4-ethyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide; (R)-4-Ethyl-3-((tert-butoxy)carbonyl)-1,2,3-oxathiazolidine 2,2-dioxide; (R)-N-Boc-4-ethyl-1,2,3-oxathiazolidine 2,2-dioxide; tert-Butyl (4R)-4-ethyl-2,2-dioxo-1,2,3-oxathiazolidine-3-carboxylate; (R)-Boc-4-ethyl-oxathiazolidine dioxide; 1417287-40-1; (R)-configuration oxathiazolidine dioxide derivative.
EINECS	Contact for details

Quality Control

Every batch of (R)-tert-Butyl 4-Ethyl-1,2,3-Oxathiazolidine-3-Carboxylate 2,2-Dioxide is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.