Description

5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery. This compound serves as a critical building block for the synthesis of novel, biologically active molecules, particularly kinase inhibitors. It is primarily needed by research and development teams in the pharmaceutical and biotechnology industries for the development of new therapeutic agents targeting various diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new drug candidates.
• Biochemical Tool Compound: Serves as a core scaffold for developing chemical probes to study specific biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazolo[3,4-B]Pyridin-3-Amine
CAS No.	1416714-23-2
Molecular Formula	C11H13BrN4O
Molecular Weight	297.15 g/mol
Synonyms	5-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-amine; 1H-Pyrazolo[3,4-b]pyridin-3-amine, 5-bromo-1-(tetrahydro-2H-pyran-2-yl)-; 5-Bromo-1-THP-1H-pyrazolo[3,4-b]pyridin-3-amine; 5-Bromo-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridin-3-amine; THP-protected 5-bromopyrazolopyridinamine; CAS 1416714-23-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazolo[3,4-B]Pyridin-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.