Description

7-Bromo-3-iodoquinoline is a high-purity halogenated quinoline derivative, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents, makes it an exceptionally valuable intermediate for constructing complex molecules through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional materials. Its reliable quality and consistent performance are paramount for ensuring successful downstream applications and process scalability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline scaffold for bioactivity.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials due to its electron-rich aromatic system.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira couplings, where the bromine and iodine atoms offer orthogonal reactivity for sequential functionalization.
• Ligand Synthesis: Utilized in the preparation of novel nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or tag in bioconjugation and the development of molecular imaging agents.

Basic Information

Item	Detail
Product Name	7-Bromo-3-iodoquinoline
CAS No.	1416440-61-3
Molecular Formula	C9H5BrIN
Molecular Weight	333.95 g/mol
Synonyms	3-Iodo-7-bromoquinoline; Quinoline, 7-bromo-3-iodo-; 7-Bromo-3-iodo-quinoline; 1416440-61-3; 7-Br-3-I-quinoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-iodoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.