Description

2-Amino-3-Iodo-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique molecular architecture, which combines an amino group, a nitro group, an iodine substituent, and a carboxylic acid moiety on a benzene ring, enabling diverse chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptors or enzymes.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its reactive halogen and functional group diversity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers, dyes, and advanced organic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) where the iodine atom acts as an excellent leaving group.
• Academic & R&D: A valuable reagent for methodological studies and the discovery of new synthetic pathways in university and corporate research laboratories.
• Ligand & Catalyst Development: The amino and carboxylic acid groups make it a candidate for constructing chelating ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Amino-3-Iodo-5-Nitrobenzoic Acid
CAS No.	1416440-54-4
Molecular Formula	C7H5IN2O4
Molecular Weight	308.03 g/mol
Synonyms	3-Iodo-5-nitroanthranilic acid; Benzoic acid, 2-amino-3-iodo-5-nitro-; 2-Amino-3-iodo-5-nitrobenzoic acid; 5-Nitro-3-iodoanthranilic acid; AI5NBA; 1416440-54-4; Anthranilic acid, 3-iodo-5-nitro-
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Iodo-5-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your application. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider using an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.