Description

Spiro[3.3]heptan-2-amine hydrochloride is a high-purity organic building block featuring a unique spirocyclic amine structure. This compound is valued for its rigid, three-dimensional geometry, which is crucial for modulating the physicochemical properties and biological activity of advanced molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, drug discovery, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry: Used in hit-to-lead and lead optimization campaigns to introduce conformational restraint and improve the potency, selectivity, and metabolic stability of drug candidates.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology: Employed as a scaffold or linker for developing molecular probes and tools to study biological pathways and protein interactions.
• Material Science: Potential monomer or additive for creating specialty polymers with unique thermal or mechanical properties derived from its spirocyclic core.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, particularly in the construction of complex, strained ring systems.

Basic Information

Product Name	Spiro[3.3]heptan-2-amine hydrochloride
CAS No.	1416439-08-1
Molecular Formula	C7H12ClN
Molecular Weight	145.63 g/mol
Synonyms	Spiro[3.3]heptan-2-amine HCl; 2-Aminospiro[3.3]heptane hydrochloride; 2-Azaspiro[3.3]heptane, hydrochloride (1:1); 2-Spiro[3.3]heptylamine hydrochloride; Spiro[3.3]heptane-2-amine hydrochloride; 1416439-08-1; 2-Amino-spiro[3.3]heptane hydrochloride
EINECS	Contact for details

Quality Control

Our Spiro[3.3]heptan-2-amine hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.