Description

1,2,3,4-Tetrahydro-2,6-Naphthyridine Hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in modern pharmaceutical research and development. Its value lies in its unique fused bicyclic structure, which is a privileged scaffold for designing novel bioactive molecules, particularly in central nervous system (CNS) and oncology drug discovery. This advanced pharmaceutical intermediate is essential for medicinal chemists and R&D teams in the pharmaceutical, biotechnology, and fine chemical synthesis sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Employed in the research of potential therapeutics for neurological disorders, leveraging the naphthyridine core's affinity for relevant biological targets.
• Oncology Research: Serves as a building block for developing kinase inhibitors and other targeted cancer therapies.
• Chemical Biology: Utilized as a probe or tool compound to study enzyme function and biological mechanisms.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex, high-value organic molecules.

Basic Information

Item	Detail
Product Name	1,2,3,4-Tetrahydro-2,6-Naphthyridine Hydrochloride
CAS No.	1416352-01-6
Molecular Formula	C8H11ClN2
Molecular Weight	170.64 g/mol
Synonyms	2,6-Naphthyridine, 1,2,3,4-tetrahydro-, hydrochloride; 1,2,3,4-Tetrahydro-2,6-naphthyridine HCl; 1,2,3,4-Tetrahydro-2,6-naphthyridine monohydrochloride; 2,6-Naphthyridine, 1,2,3,4-tetrahydro-, monohydrochloride; THN-HCl; 1,2,3,4-Tetrahydro-2,6-diazanaphthalene hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-2,6-Naphthyridine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.