Description

6-Bromo-7-Fluoroindolin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated indolinone core structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for developing tool compounds and molecular probes to study biological pathways.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Investigated as a building block for specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	6-Bromo-7-Fluoroindolin-2-One
CAS No.	1415580-09-4
Molecular Formula	C8H5BrFNO
Molecular Weight	230.04 g/mol
Synonyms	6-Bromo-7-fluoro-2,3-dihydro-1H-indol-2-one; 6-Bromo-7-fluoroindolin-2-one; 7-Fluoro-6-bromoindolin-2-one; 2-Indolinone, 6-bromo-7-fluoro-; 1H-Indol-2-one, 6-bromo-7-fluoro-2,3-dihydro-; 6-Bromo-7-fluoro-2-indolinone; 1415580-09-4; 6-Br-7-F-indolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Fluoroindolin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.