Description

(S)-But-3-Yn-2-Amine Hydrochloride is a chiral amine hydrochloride salt featuring a terminal alkyne functional group. This unique molecular architecture makes it a high-value building block for the synthesis of complex, optically active molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder research.
• Agrochemical Synthesis: Used in the creation of novel, optically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation and Probe Chemistry: The alkyne group enables efficient click chemistry reactions (e.g., CuAAC) for labeling biomolecules and creating diagnostic probes.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	(S)-But-3-Yn-2-Amine Hydrochloride
CAS No.	1414960-66-9
Molecular Formula	C₄H₈ClN
Molecular Weight	105.56 g/mol
Synonyms	(S)-3-Butyn-2-amine hydrochloride; (S)-1-Methyl-2-propynylamine hydrochloride; (S)-But-3-yn-2-aminium chloride; (2S)-But-3-yn-2-amine hydrochloride; (S)-2-Aminobut-3-yne hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-But-3-Yn-2-Amine Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chiral purity and chemical identity. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (ee), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.