Description

Methyl Exo-8-Azabicyclo[3.2.1]Octan-2-Carboxylate is a specialized bicyclic organic compound featuring a nitrogen bridgehead, serving as a crucial synthetic intermediate in advanced organic chemistry. Its rigid, three-dimensional scaffold is highly valued for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within the central nervous system (CNS) and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of tropane alkaloid derivatives and other pharmacologically active nitrogen-containing heterocycles.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies in drug discovery programs targeting neurological disorders.
• Process Chemistry: Used in the development and scale-up of synthetic routes for complex drug candidates under Good Manufacturing Practice (GMP) guidelines.
• Chemical Biology: Utilized as a molecular probe or precursor for labeled compounds in biochemical and receptor binding studies.
• Academic & Institutional Research: Serves as a starting material for novel methodological studies in organic synthesis and catalysis.
• Custom Synthesis: Basis for producing bespoke, high-value fine chemicals and advanced intermediates for client-specific projects.

Basic Information

Product Name	Methyl Exo-8-Azabicyclo[3.2.1]Octan-2-Carboxylate
CAS No.	1408075-58-0
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Methyl 8-azabicyclo[3.2.1]octane-2-carboxylate (exo-); Methyl exo-8-azabicyclo[3.2.1]octane-2-carboxylate; Methyl exo-8-azabicyclo[3.2.1]octan-2-carboxylate; 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester, exo-; Methyl 2-exo-carboxy-8-azabicyclo[3.2.1]octane; Tropane-2-carboxylic acid methyl ester (exo-); exo-Methyl tropane-2-carboxylate; 8-Azabicyclo[3.2.1]octane-2-methanol, α-carbomethoxy-, exo-
EINECS	Contact for details

Quality Control

Our Methyl Exo-8-Azabicyclo[3.2.1]Octan-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data, including HPLC, GC, and NMR spectra, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and supplied upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.