Description

8-Boc-2,8-Diaza-Spiro[4.5]Decane Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a protected diaza-spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of complex bioactive molecules targeting central nervous system disorders. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, especially those with spirocyclic architectures for enhanced binding affinity and metabolic stability.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for developing new pharmacophores targeting GPCRs and other neurological receptors.
• Preclinical Development: Serves as a critical starting material for producing Active Pharmaceutical Ingredients (APIs) in milligram to kilogram scales for toxicology and formulation studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions within biological systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis projects requiring high-fidelity, protected heterocyclic intermediates.

Basic Information

Item	Details
Product Name	8-Boc-2,8-Diaza-Spiro[4.5]Decane Hemioxalate
CAS No.	1408074-53-2
Molecular Formula	C15H26N2O5
Molecular Weight	314.38 g/mol
Synonyms	tert-Butyl 2,8-diaza-spiro[4.5]decane-8-carboxylate hemioxalate; 2,8-Diaza-spiro[4.5]decane-8-carboxylic acid, 1,1-dimethylethyl ester, hemioxalate; 8-(tert-Butoxycarbonyl)-2,8-diazaspiro[4.5]decane hemioxalate; 8-Boc-2,8-diazaspiro[4.5]decane oxalic acid salt (1:0.5); BOC-DAD Hemioxalate; CAS 1408074-53-2
EINECS	Contact for details

Quality Control

Every batch of 8-Boc-2,8-Diaza-Spiro[4.5]Decane Hemioxalate is manufactured under strict quality management systems. We guarantee high purity and batch-to-batch consistency through rigorous analytical controls, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.