Description

(3S)-3-(Benzenesulfonyl)Pyrrolidine is a high-purity chiral sulfonamide building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where the specific 3S configuration can influence biological activity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and protein function.
• Peptidomimetics: The pyrrolidine sulfonamide structure is valuable for creating conformationally constrained peptide analogs.
• Material Science: Investigated as a monomer or additive for specialty polymers with specific optical or chemical properties.

Basic Information

Product Name	(3S)-3-(Benzenesulfonyl)Pyrrolidine
CAS No.	1408057-40-8
Molecular Formula	C10H13NO2S
Molecular Weight	211.28 g/mol
Synonyms	(3S)-3-(Phenylsulfonyl)pyrrolidine; (S)-3-(Benzenesulfonyl)pyrrolidine; (S)-3-(Phenylsulfonyl)pyrrolidine; Pyrrolidine, 3-(phenylsulfonyl)-, (3S)-; 1408057-40-8; (S)-3-(Benzenesulphonyl)pyrrolidine; (3S)-3-(Benzenesulphonyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (3S)-3-(Benzenesulfonyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.