Description

[1,3-Bis(2,4,6-Trimethylphenylimidazolidin-2-Ylidene)](Tricyclohexylphosphine)-(2-Oxobenzylidene)Ruthenium(II) Chloride Latmet is a highly specialized, second-generation Grubbs-Hoveyda type olefin metathesis catalyst. This compound matters for its exceptional thermal stability and functional group tolerance, enabling complex synthetic transformations under mild conditions. It is a critical reagent for researchers and process chemists in pharmaceutical development, advanced materials science, and specialty chemical synthesis, where precise and efficient carbon-carbon double bond formation is required.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key ring-closing metathesis (RCM), cross metathesis (CM), and ring-opening metathesis polymerization (ROMP) steps in the production of active pharmaceutical ingredients (APIs).
• Advanced Polymer & Material Science: Facilitating the ROMP of strained cyclic olefins to create novel polymers with tailored properties for specialty coatings, elastomers, and functional materials.
• Agrochemical Research: Used in the synthesis of complex molecular architectures for novel crop protection agents and plant growth regulators.
• Fine Chemical & Fragrance Manufacturing: Applied in the synthesis of high-value, complex olefinic compounds where selectivity and yield are paramount.
• Academic & Industrial R&D: Serving as a premium catalyst for methodological development and exploring new metathesis pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	[1,3-Bis(2,4,6-Trimethylphenylimidazolidin-2-Ylidene)](Tricyclohexylphosphine)-(2-Oxobenzylidene)Ruthenium(II) Chloride Latmet
CAS No.	1407229-58-6
Molecular Formula	C48H66ClN2OPRu
Molecular Weight	876.52 g/mol
Synonyms	Latmet Catalyst; Grubbs-Hoveyda II Catalyst (Latent); Hoveyda-Grubbs Catalyst 2nd Generation (Latent); (2-Oxobenzylidene)Ruthenium(II) Chloride Complex; [1,3-Bis(2,4,6-Trimethylphenyl)imidazolidin-2-ylidene]dichloro(o-isopropoxyphenylmethylene)ruthenium(II) (Latent Form); Latent Metathesis Catalyst; Zhan Catalyst 1B (Latent); HG II Latent Catalyst
EINECS	Contact for details

Quality Control

Every batch of our [1,3-Bis(2,4,6-Trimethylphenylimidazolidin-2-Ylidene)](Tricyclohexylphosphine)-(2-Oxobenzylidene)Ruthenium(II) Chloride Latmet is manufactured and handled under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is moisture-sensitive (hygroscopic) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will lead to decomposition and loss of catalytic activity. Keep the container sealed and allow it to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to purple crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Residual Solvents (GC)	Meet ICH guidelines
Elemental Analysis	Conforms to theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.