Description

6-Bromo-Imidazo[1,2-A]Pyrazine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing bromine and a carboxylic acid functional group. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel drug candidates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Kinase Inhibitor Development: The imidazopyrazine scaffold is prevalent in compounds designed to modulate kinase activity for oncology and inflammatory diseases.
• Bioconjugation & Probe Synthesis: The carboxylic acid moiety allows for coupling to other molecules, peptides, or labels to create chemical probes for biological studies.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development of robust, scalable synthetic routes under GMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	6-Bromo-Imidazo[1,2-A]Pyrazine-3-Carboxylic Acid
CAS No.	1404480-51-8
Molecular Formula	C7H4BrN3O2
Molecular Weight	242.03 g/mol
Synonyms	6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid; 6-Bromo-3-carboxyimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine-3-carboxylic acid, 6-bromo-; 1404480-51-8; 6-Bromoimidazo[1,2-a]pyrazine-3-carboxylic acid; 6-Bromo-1H-imidazo[1,2-a]pyrazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-Imidazo[1,2-A]Pyrazine-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from strong light sources. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.