Description

7-Bromo-3,7B-Dihydro-1H-Cyclopropa[C]Quinolin-2(1Ah)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused cyclopropaquinoline structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems due to its reactive bromine and ketone functional groups.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	7-Bromo-3,7B-Dihydro-1H-Cyclopropa[C]Quinolin-2(1Ah)-One
CAS No.	1404431-47-5
Molecular Formula	C11H8BrNO
Molecular Weight	250.09 g/mol
Synonyms	7-Bromo-1a,7b-dihydro-1H-cyclopropa[c]quinolin-2(1aH)-one; 7-Bromocyclopropa[c]quinolin-2(1H)-one; 7-Bromo-3,7b-dihydro-1H-cyclopropa[c]quinolin-2(1aH)-one; 1404431-47-5; 7-Bromo-1a,7b-dihydrocyclopropa[c]quinoline-2(1H)-one; 7-Bromo-1a,7b-dihydro-1H-cyclopropa[c]quinolin-2-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-3,7B-Dihydro-1H-Cyclopropa[C]Quinolin-2(1Ah)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.