Description

6-Bromo-7-Chloro-3,4-Dihydroquinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This heterocyclic compound serves as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile quinolinone scaffold.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with potential novel modes of action.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic systems and functionalized quinoline derivatives.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying enzyme inhibition or receptor binding.

Basic Information

Product Name	6-Bromo-7-Chloro-3,4-Dihydroquinolin-2(1H)-One
CAS No.	1404367-56-1
Molecular Formula	C9H7BrClNO
Molecular Weight	260.52 g/mol
Synonyms	6-Bromo-7-chloro-1,2,3,4-tetrahydroquinolin-2-one; 6-Bromo-7-chloro-3,4-dihydro-2(1H)-quinolinone; 7-Chloro-6-bromo-1,2,3,4-tetrahydroquinolin-2-one; 2(1H)-Quinolinone, 6-bromo-7-chloro-3,4-dihydro-; 6-Bromo-7-chloro-1,2,3,4-tetrahydro-2-quinolone; 6-Bromo-7-chloro-3,4-dihydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Chloro-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.