Description

n-Methyl-n-(Oxan-4-Yl)Azetidin-3-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its azetidine and tetrahydropyran (oxane) structural motifs. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule therapeutics. It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and academic research institutions engaged in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting G protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to develop new therapeutic agents.
• Preclinical Drug Development: Serves as a critical raw material for producing compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting point for the custom manufacturing of specialized analogs and derivatives for client-specific research programs.

Basic Information

Product Name	n-Methyl-n-(Oxan-4-Yl)Azetidin-3-Amine Dihydrochloride
CAS No.	1403767-06-5
Molecular Formula	C9H18N2O • 2HCl
Molecular Weight	251.17 g/mol (as free base: 170.25 g/mol)
Synonyms	1-Methyl-1-(tetrahydro-2H-pyran-4-yl)azetidin-3-amine dihydrochloride; 3-Amino-1-methyl-1-(oxan-4-yl)azetidine dihydrochloride; 1-Methyl-1-(tetrahydro-4H-pyran-4-yl)-3-azetidinamine dihydrochloride; 1-Methyl-1-(tetrahydropyran-4-yl)azetidin-3-amine dihydrochloride; 1403767-06-5; n-Methyl-n-(tetrahydro-2H-pyran-4-yl)azetidin-3-amine dihydrochloride
EINECS	Contact for details

Quality Control

Our n-Methyl-n-(Oxan-4-Yl)Azetidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.