Description

1-(Benzyloxy)-5-Bromo-4-Chloro-2-Nitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective chemical transformations, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for structural diversity.
• Organic Synthesis Reagent: Serves as a versatile precursor in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution (SNAr) for creating complex aromatic systems.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and pigments due to its electron-accepting nitro group and modifiable aromatic core.
• Chemical Biology & Proteomics: Can be utilized as a scaffold or linker for developing chemical probes, enzyme inhibitors, or bioconjugation reagents.

Basic Information

Product Name	1-(Benzyloxy)-5-Bromo-4-Chloro-2-Nitrobenzene
CAS No.	1403483-74-8
Molecular Formula	C13H9BrClNO3
Molecular Weight	342.57 g/mol
Synonyms	5-Bromo-4-chloro-2-nitro-1-(phenylmethoxy)benzene; 1-Benzyloxy-5-bromo-4-chloro-2-nitrobenzene; Benzene, 1-(benzyloxy)-5-bromo-4-chloro-2-nitro-; 5-Bromo-4-chloro-2-nitrophenyl benzyl ether; 2-Nitro-5-bromo-4-chlorophenyl benzyl ether; 4-Chloro-5-bromo-2-nitrophenyl benzyl ether
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxy)-5-Bromo-4-Chloro-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.