Description

n-Cyclopentyl 4-Bromo-2-Fluorobenzylamine, Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzylamine structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo-fluoro substitution patterns into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of bromine and fluorine atoms on bioactivity and metabolic stability.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides or pesticides, leveraging the halogenated aromatic system.
• Ligand Synthesis: Utilized for preparing specialized ligands for catalysis or molecular recognition applications in chemical synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Employed in university and institutional labs for methodological development and exploratory organic synthesis.

Basic Information

Product Name	n-Cyclopentyl 4-Bromo-2-Fluorobenzylamine, Hcl
CAS No.	1403483-57-7
Molecular Formula	C12H16BrFN•HCl
Molecular Weight	308.63 g/mol (Free base: 272.17)
Synonyms	4-Bromo-2-fluorobenzyl(cyclopentyl)amine hydrochloride; 1-[(4-Bromo-2-fluorophenyl)methyl]cyclopentanamine hydrochloride; N-Cyclopentyl-1-(4-bromo-2-fluorophenyl)methanamine hydrochloride; (4-Bromo-2-fluorobenzyl)(cyclopentyl)amine HCl; Benzylamine, N-cyclopentyl-4-bromo-2-fluoro-, hydrochloride; Cyclopentyl(4-bromo-2-fluorobenzyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Cyclopentyl 4-Bromo-2-Fluorobenzylamine, Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for water content, to ensure it meets the stringent requirements for advanced synthetic intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.